It isn’t a cure (there is no cure for Alzheimer’s or related dementias) but studies have shown memantine treats symptoms by improving memory, awareness, and concentration. I'd love to try it out! It’s basically a mental condition where an individual experiences bothersome, intrusive, and worrisome thoughts that elicit a feeling of discomfort and/or fear that often leads to obsessive-compulsive behaviors. NAC really shut down the internal monologue that I associate with my obsessive thinking. The analysis included double-blind, randomized, placebo-controlled trials of memantine in MDD and BD. Read More. Results: Memantine is the compound most consistently showing a positive effect as an augmentation therapy in OCD. Started at 600mg am 600 mg p.m went up to 1800 mg am, 1800 mg pm. It’s pretty surprising when I take a look through the community though I’ve never tried it myself. Current psychotherapy and medication treatments for OCD can be of help to many who suffer from the disorder. I have anxiety and depression as well, but the OCD is the worst. I am currently on vyvanse which helps the OCD somewhat (can make it worse though), gabapentin 600mg 3x a day, propanalol 20mg 3x, baclofen 20mg 3x, lamictal 100mg, and melatonin for sleep. Researchers examined whether adjunctive gabapentin or memantine and standard treatment with a selective serotonin-reuptake inhibitor (SSRI) might lead to further improvements in patients with OCD. Common Questions and Answers about Memantine and ocd. Request PDF | An open-label trial of memantine in treatment-resistant obsessive-compulsive disorder | Background:Obsessive-compulsive disorder (OCD) is often refractory to treatment. Although the risk of memantine abuse is very low, other NMDA receptor antagonists, such as phencyclidine and ketamine, are well known to drug users. I read some of your previous posts on it I suffer with over self consciousness too, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425334/. I seriously doubt memantine's NMDA properties were of any benefit for me, probably because I don't have anxiety or other signs of glutaminergic over-activity to begin with. Do you cycle it at all? This is why it's seen as so overrated by some, because there are so many vendors selling it in ridiculously low concentrations or lying and there's still THC in the product (if from a dispensary). It is ... A study examining self-reported misuse of memantine on the social network reddit shown that the drug was used as a recreational drug and as a nootropic, but also that it was misused in various illnesses as self-medication without strong scientific basis. Hold liquid in mouth and do not swallow for at least 2 minutes. I.e. Chills out my mind and relieves the muscle tension that develops when I ruminate negative thoughts before bed. 2. You will be given a small dose when you first start treatment. It does not however make you feel high; there is a slight "shift" in perception but in no way are you intoxicated or slowed down. Out of curiosity, what has your experience been. Quite the contrary. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. The association of OCD-schizotypal comorbidity with the beneficial effect of memantine is noteworthy in view of a pertinence of glutamatergic dysfunction in both OCD and schizophrenia spectrum disorders . Its name is derived from its structure; 3,5-dimethyladamantan-1-amine. Towards New Medications for Refractory OCD. Also, good for inducing the type of ADHD left brained thinking that helps get things done instead of listening to the internal monologue. Towards New Medications for Refractory OCD. In the meantime, although, I don't have clinically diagnosed OCD, I have no doubt I am on the spectrum. 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